–noun
| 1. | a change or variation occurring in the course of something. |
| 2. | interchange or alternation, as of states or things. |
| 3. | vicissitudes, successive, alternating, or changing phases or conditions, as of life or fortune; ups and downs: They remained friends through the vicissitudes of 40 years. |
| 4. | regular change or succession of one state or thing to another. |
| 5. | change; mutation; mutability. |
from dictionary.com
